Synthesis and Medicinal Chemistry

It is of paramount importance to have drugs that are efficient, selective and without serious side effects. The MSc Eng programme in Synthesis and Medicinal Chemistry offers competences in medicinal chemistry and organic synthesis, and offers the opportunity to work in drug design and development.

The programme will teach you about the process of producing a pharmaceutical from the initial idea to the final drug used in the treatment of disease.

Designing and executing a short and efficient synthetic route to a desired chemical substance is vital to a drug- development programme. This requires an in-depth knowledge of theoretical and practical organic chemistry, which is a major part of the MSc Eng programme. You also gain experience in the important field of molecular modelling.

You will have the opportunity to use your knowledge in research and development projects relevant to drug-development and production. Some projects will be carried out in close collaboration with industrial partners from pharmaceutical companies.

Program Provisions

To complete the study line in Synthesis and Medicinal Chemistry, the student must fulfil the following requirements:

Have passed General Competence Courses adding up to at least 30 ECTS points.
Have passed Technological Specialization Courses adding up to at least 30 ECTS points.
Have performed a Master Thesis of at least 30 ECTS within Synthesis and Medicinal Chemistry.
Have passed a sufficient number of Elective Courses to bring the total number of ECTS points of the entire study to 120 points.

Contact

Mads Hartvig Clausen Professor Department of Chemistry Phone: +45 45252131 mhc@kemi.dtu.dk

Study line Synthesis and Medicinal Chemistry

Polytechnic foundation courses (5 ECTS)

The following course is mandatory

42501	Innovation in Engineering (Polytechnical Foundation)	5	point	June
or
42504	Innovation in Engineering (Polytechnical Foundation)	5	point	August
or
42500	Innovation in Engineering (Polytechnical Foundation)	5	point	January

Students with advanced innovation competences may take one of the following courses as an alternative to 42500/42501/42504

42505	Facilitating Innovation in Multidisciplinary Teams	5	point	August
or
42503	Facilitating Innovation in Multidisciplinary Teams	5	point	June
or
42502	Facilitating Innovation in Multidisciplinary Teams	5	point	January

Programme specific courses (55 ECTS)

Innovation course II - choose 5 ECTS among the following courses - if you take more than 5 ECTS in this group they will count as electives:

26620	Chemistry and Innovation	5	point	June
28311	Chemical and Biochemical Product Design	5	point	Autumn E2A (Mon 13-17)
28485	Biobusiness and Process Innovation	5	point	Autumn E1B (Thurs 13-17)

Core competence courses - choose 20 ECTS among the following courses:

26231	Physical Chemistry 3	5	point	Spring F5B (Wed 13-17)
26317	Instrumental chemical analysis	5	point	Spring F2B (Thurs 8-12)
26422	Biomolecular Chemistry	5	point	Autumn E3A (Tues 8-12)
26433	Organic Chemistry 3	5	point	Autumn E4A (Tues 13-17)
28212	Polymer Chemistry	5	point	Spring F3A (Tues 8-12)
28315	Applied Colloid and Surface Chemistry	5	point	E7 (Tues 18-22)
47339	Solid state and structural chemistry	5	point	Autumn E1A (Mon 8-12)
or
26134	Advanced Inorganic Chemistry (Inorganic Chemistry 3)	5	point	Autumn E5A (Wed 8-12)

If the total Core Competence Courses passed exceed 20 ECTS points, the surplus courses may be used in fulfilling the requirement for the rest of the programme specific courses

Choose in total 30 ECTS among the rest of the programme specific courses:

The following courses are mandatory to fullfill the requirements of the studyline:

26416	Laboratory Course in Organic Synthesis	5	point	January
26444	Organic Chemistry 4	10	point	Spring F4 (Tues 13-17, Fri 8-12)
26446	Advanced Medicinal Chemistry	5	point	Spring F2A (Mon 13-17)

Choose at least 10 points among the following courses:

22210	Immune System in Health and Disease	5	point	Autumn E1B (Thurs 13-17)
26245	Applied computational chemistry	5	point	June
26426	Introduction to Medicinal Chemistry	5	point	Spring F2B (Thurs 8-12)
26438	NMR Spectroscopy	5	point	Autumn E4B (Fri 8-12)
26455	Physical Organic Chemistry and Reaction Mechanisms	5	point	June
27430	Eukaryotic cell biology	5	point	Spring F3A (Tues 8-12)

Elective Courses

The following courses are proposals for the studyline:

02450	Introduction to Machine Learning and Data Mining	5	point	Spring F4A (Tues 13-17), Autumn E4A (Tues 13-17)
22235	Drug delivery	5	point	Spring F5B (Wed 13-17)
22237	Preclinical drug development	5	point	Autumn E5A (Wed 8-12)
26436	Pharmaceutical Drug Development	10	point	Autumn E1 (Mon 8-12, Thurs 13-17)
27423	Metabolomics and proteomics	5	point	Autumn E3A (Tues 8-12)
28316	Laboratory Course in Colloid and Surface Chemistry	5	point	January
63850	Sustainable Business in the pharmaceutical industry on emerging markets and developing countries - Access to health care	7.5	point	Autumn E4A (Tues 13-17) and Autumn E2B (Thurs 8-12)